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AbbVie Reports Results of Rinvoq (upadacitinib) in P-II/III SELECT-AXIS 1 Study for Patients with Ankylosing Spondylitis

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AbbVie Reports Results of Rinvoq (upadacitinib) in P-II/III SELECT-AXIS 1 Study for Patients with Ankylosing Spondylitis

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  • The P-II/III SELECT-AXIS 1 Trial involves assessing of Rinvoq (15mg- qd) vs PBO in patients with active AS who are bDMARD-naïve and had an inadequate response to at least two NSAIDs or intolerance to/contraindication for NSAIDs- evaluating its safety and efficacy
  • The study resulted in achieving 1EP as ASAS 40 @14 wks. (52% vs 26%)- no new safety risks detected- Presented at ACR/ARP Annual Meeting 2019
  • Rinvoq is a JAK inhibitor- currently being evaluated in P-III studies for psoriatic arthritis- Crohn's disease- atopic dermatitis- UC and giant cell arteritis and is an approved therapy for adult patients with moderately to severely active RA. Rinvoq has also received CHMP’s positive opinion and is currently awaiting for EC’s approval

Click here to­ read full press release/ article | Ref: AbbVie  | Image: AbbVie


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